ncRNA name | hsa-miR-15a |
ncRNA Category | miRNA |
Disease name | diabetic retinopathy (DR) |
Species | Homo sapiens |
Tissues/Cell_line | human retinal endothelial cells (HRECs) |
Methods | transfection, Western blot |
Expression pattern | down-regulated |
Functional description | miR-15a/16 maintain the retinal endothelial cell barrier by reducing TGFbeta3/VEGF signaling and increasing levels of key tight junction proteins. |
PubMed ID | 28774775 |
Year | 2017 |
Title | miR-15a/16 inhibits TGF-beta3/VEGF signaling and increases retinal endothelial cell barrier proteins. |
Drug-related ncRNA | NO |
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